Tablet Presentation
Each film coated sustained release tablet Contains:
Oxaceprol 600 mg
Oxaceprol is used to the treat the pain and swelling of the knee and hip joints and other associated inflammatory conditions.
Oxaceprol inhibits the white blood cells from adhesion and migration.
Osteoporosis is the disorder of joints that affects the cartilages and both the small and large joints.
Indications
- In osteoarthritis
- Inflammatory connective tissue
Mechanism of Action
It selectively inhibits the extraversion of neutrophil white blood cells. it reduces the adhesion of leucocytes to the endothelium.
Pharmacokinetics
Absorption-
It is absorbed orally
Protein Binding-
It is about 79% bound to plasma proteins
Metabolism-
It is metabolized in the liver
Excretion-
It is excreted via urine
Side Effects
- Nausea
- Headache
- Abdominal pain
- Indigestion
- Skin rashes
- Dry mouth
- Constipation
Contraindications
- Contraindicated during pregnancy
- Contraindicated during breast feeding
Drug Interactions
- Methotrexate
- Lithium
- Antihypertensive
- Vitamin K
- Anticoagulant